Simian hemorrhagic fever virus: Recent advances
نویسندگان
چکیده
منابع مشابه
Ebola Hemorrhagic Fever-recent Outbreak
HISTORY ABSTRACT: Ebola Hemorrhagic Fever (EHF) is a deadly infection which has no cure till today. Treating the symptoms and supportive care are the main stay in the management of the disease. There are some treatments and vaccines in initial stage of development but, they are never tested on humans. BACKGROUND:According to New York Times recent outbreak of Ebola Hemorrhagic fever (EHF) or Ebo...
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Diseases caused by the dengue viruses comprise of the classical form of dengue fever (DF) and the more severe dengue haemorrhagic fever (DHF) sometimes accompanied by the dengue shock syndrome (DSS). These diseases continue to pose an important public health threat in many parts of the tropical world 3 2 . In recent years, DF outbreaks have occurred in India (1982) and Northern Australia (1981)...
متن کاملEach of the eight simian hemorrhagic fever virus minor structural proteins is functionally important.
The simian hemorrhagic fever virus (SHFV) genome differs from those of other members of the family Arterivirus in encoding two adjacent sets of four minor structural protein open reading frames (ORFs). A stable, full-length, infectious SHFV-LVR cDNA clone was constructed. Virus produced from this clone had replication characteristics similar to those of the parental virus. A subgenomic mRNA was...
متن کاملFunctional analyses of the three simian hemorrhagic fever virus nonstructural protein 1 papain-like proteases.
UNLABELLED The N-terminal region of simian hemorrhagic fever virus (SHFV) nonstructural polyprotein 1a is predicted to encode three papain-like proteases (PLP1α, PLP1β, and PLP1γ). Catalytic residues and cleavage sites for each of the SHFV PLP1s were predicted by alignment of the SHFV PLP1 region sequences with each other as well as with those of other arteriviruses, and the predicted catalytic...
متن کاملExceptional simian hemorrhagic fever virus diversity in a wild African primate community.
Simian hemorrhagic fever virus (SHFV) is an arterivirus that causes severe disease in captive macaques. We describe two new SHFV variants subclinically infecting wild African red-tailed guenons (Cercopithecus ascanius). Both variants are highly divergent from the prototype virus and variants infecting sympatric red colobus (Procolobus rufomitratus). All known SHFV variants are monophyletic and ...
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ژورنال
عنوان ژورنال: Virus Research
سال: 2015
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2014.11.024